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style=\"font-size: 15px;\">滤泡性淋巴瘤（follicular lympoma，FL)是一类惰性病程的淋巴肿瘤，来源于滤泡生发中心的成熟B细胞，恶性度较低。多见于中老年患者，20岁以下发病者少见，男女比例1:1.7。\u003C\u002Fspan>\u003C\u002Fp>","⚕️","2026-08-03",{"key":90,"title":91,"html":92,"icon":93,"updatedAt":88},"cause","病因","\u003Cdiv>\u003Cspan style=\"font-size: 15px;\"> 确诊时患者多已处于进展期，仅1\u002F3的患者处于Ⅰ、Ⅱ期。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">1、淋巴结肿大浅表淋巴结肿大最为常见，可累及全身各个浅表区域；有时也可累及腹膜后、肠系膜、回肠等部位的淋巴结。原发性纵隔受累少见。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">2、可伴有脾大，但较少出现全身症状。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">3、骨髓40%~70%的患者可发生骨髓受累。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">4、淋巴结外表现：原发的淋巴结外受侵犯少见，但皮肤、乳房、睾九、胃肠道等均可累及，特别是十二指肠或小肠，可以表现为小息肉。\u003C\u002Fspan>\u003C\u002Fdiv>","🧬",{"key":95,"title":96,"html":97,"icon":98,"updatedAt":88},"symptom","症状表现","\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">如果医生怀疑您患有滤泡性淋巴瘤，首先会对您做全面的体格检查。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cp>\u003Cspan style=\"font-size: 15px;\">诊断滤泡性淋巴瘤的常规检查包括：\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">\u003Cbr\u002F>\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">血液检查：用于观察不同类型血细胞的数量和形态。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">\u003Cbr\u002F>\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">骨髓检查：用于观察骨骼内的造血组织。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">\u003Cbr\u002F>\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">影像学检查：如胸部X线检查用于观察肺部及其周围区域的情况；CT用于观察身体各部位的横断面图像，您可能需要接受胸部、腹部和（或）盆腔部位的扫描；PET\u002FCT使用特殊的摄像机和放射性示踪剂，检查的灵敏度更高。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">\u003Cbr\u002F>\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\"> 细胞免疫学检查：例如流式细胞分析检测患者淋巴结、骨髓、外周血或脾组织细胞表面蛋白。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 15px;\">\u003Cbr\u002F>\u003C\u002Fspan>\u003C\u002Fp>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">基因检测：滤泡性淋巴瘤可见染色体和基因异常，可利用细胞遗传学方法检查患者有无染色体数量或结构异常。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>","📋",{"key":100,"title":101,"html":102,"icon":103,"updatedAt":88},"exam","检查方式","\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">无治疗指征的滤泡性淋巴瘤（FL）患者可以观察等待，直至疾病进展再进行治疗。滤泡性淋巴瘤的治疗包括化疗、放疗、靶向药物治疗和造血干细胞移植。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">·放疗\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">放疗利用高能射线治疗肿瘤，可单独使用，也可与其他癌症治疗方法联用。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">滤泡性淋巴瘤（FL）对放疗完全反应率高，反映持续时间长。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">·化疗\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">化疗药物可以单独使用，也可与其他化疗药物或治疗方法联用。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">化疗的副作用取决于您所使用的化疗药物。常见的副作用包括恶心和脱发。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">·靶向药物\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">利妥昔单抗是一种单克隆抗体，它能够与B细胞结合，使免疫系统更容易识别B细胞并将其清除。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cbr\u002F>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">·造血干细胞移植\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">医生利用大剂量的化疗和放疗来抑制骨髓，随后将从患者自身或供者身上采集的健康的骨髓干细胞输入患者的血液中。干细胞会随血液循环进入骨骼并重建骨髓。\u003C\u002Fspan>\u003C\u002Fdiv>\u003Cdiv>\u003Cspan style=\"font-size: 15px;\">接受骨髓移植的患者发生感染的风险可能会增加。\u003C\u002Fspan>\u003C\u002Fdiv>","🩺",{"author":105,"reviewedBy":105,"lastReviewed":105,"datePublished":105,"citations":106,"disclaimer":105},"",[107],{"title":108},"Mayo Clinic",false,1789384106375]